Incorperation of Bioenzymatic Synthesis in Total Synthesis of Natural Products

So I think I've found an area of biological chemistry that really really interests me: using enzymes in total synthesis. It seems to be a relatively new tool to pull out of the bag of synthetic tricks, but I have found papers that use a combo of bioenzymatic snytheses and traditional synthetic organic reactions (in this case, a Stille coupling), as well as a total enzymatic synthesis of this particular set of bacterial products that seem to slow down tumor formation. I'm going to write a paper for biochem about this (focusing on the biochem side instead of the synthetic side...i.e. the relevance of products and why this particular enzymatic transformation is synthetically useful as opposed to the synthetic methodology aspect...but both catch my interest). But it's really handy because enzymes do all sorts of crazy shit that we don't do well...like stereochemical control and massively concerted reactions...and additionally are pretty green (i.e. don't require large amounts of heavy metals that are a bitch to dispose of). They can only be used for very specialized transformations, so there's a lot of work that still needs to be done in this field. Also, they can be a bit of a bitch to purify, but then again, organic reactions in general can be a bitch to purify.

This seems like an area that satisfies the synthetic chemist and the biochemist in me.